Table 4.
Linear associations for MS components with U-shaped relation to head and neck cancer risk
| MS components | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Waist circumference (female) | ||||||
| <93.16 cm | 0.94[0.80, 1.11] | 0.469 | 0.94[0.80, 1.11] | 0.471 | 0.92[0.78, 1.08] | 0.311 |
| ≥93.16 cm | 1.42[1.11, 1.80] | 0.005 | 1.41[1.11, 1.80] | 0.005 | 1.47[1.15, 1.89] | 0.003 |
| HDL-C (male) | ||||||
| <1.26 mmol/L | 0.85[0.75, 0.97] | 0.013 | 0.85[0.75, 0.97] | 0.013 | 0.88[0.77, 1.00] | 0.050 |
| ≥1.26 mmol/L | 1.21[1.08, 1.36] | 0.001 | 1.22[1.09, 1.36] | 0.001 | 1.19[1.06, 1.34] | 0.003 |
| HDL-C (female) | ||||||
| <1.45 mmol/L | 0.90[0.70, 1.14] | 0.384 | 0.90[0.70, 1.14] | 0.381 | 0.91[0.71, 1.17] | 0.462 |
| ≥1.45 mmol/L | 1.05[0.88, 1.27] | 0.576 | 1.05[0.88, 1.27] | 0.567 | 1.10[0.92, 1.33] | 0.301 |
| Blood glucose | ||||||
| <4.70 mmol/L | 0.93[0.80, 1.08] | 0.330 | 0.97[0.84, 1.12] | 0.674 | 0.96[0.83, 1.11] | 0.577 |
| ≥4.70 mmol/L | 1.14[1.06, 1.22] | 0.001 | 1.10[1.02, 1.19] | 0.010 | 1.10[1.01, 1.19] | 0.022 |
| Diastolic blood pressure | ||||||
| <83 mmHg | 1.13[1.02, 1.25] | 0.022 | 1.07[0.96, 1.18] | 0.221 | 1.09[0.98, 1.21] | 0.121 |
| ≥83 mmHg | 1.03[0.94, 1.14] | 0.538 | 0.99[0.90, 1.10] | 0.917 | 0.99[0.90, 1.09] | 0.886 |
Model 1: unadjusted
Model 2: age and gender-stratified model
Model 3: additionally adjusted for education, ethnic, Index of multiple deprivation, alcohol consumption, smoking status, physical activity, fruit and vegetable intake, NASIDS use and CRP