Table 2.
Cost used in base case and sensitivity analyses
| Model input | Base case value | SA range for one-way sensitivity analyses | Distribution |
|---|---|---|---|
| Intervention cost | |||
| FeNO per patient day | 2.20 | 1.20–4.20 | γ(SD:1.08) |
| Hospitalization cost | |||
| Daily cost in pediatric ward | 95.05 | 80.23–102.01 | γ(SD:8.53) |
| Hospital length of stay (days) | 5.50 | 4.00–8.00 | γ(SD:1.04) |
| PICU related cost | |||
| Daily cost in PICU | 406.52 | 430.26–350.43 | γ(SD:18.89) |
| PICU lenght of stay (days) | 10.9 | 7.75–15.05 | γ(SD:3.26) |
| Emergency visit prior hospitalization cost | |||
| Daily cost of emergency ward | 64.3 | 51.19–71.46 | γ(SD:19.27) |
| Direct medical cost per patient-day | |||
| Specialist referrals | 10.67 | 10.31–11.01 | γ(SD:1.72) |
| Chest physiotherapy | 5.15 | 4.90–5.39 | γ(SD:1.23) |
| Chest radiography | 2.84 | 2.70–2.98 | γ(SD:0.73) |
| Others diagnostic imaging | 0.01 | 0.0–0.02. | γ(SD:0.08) |
| Complete blood cell counts | 1.12 | 1.05–1.17 | γ(SD:0.28) |
| Other laboratory tests | 4.4 | 4.23–4.47 | γ(SD:0.37) |
| Oxygen | 1.37 | 1.28–1.45 | γ(SD:0.41) |
| Nebulization | 16.23 | 1.28–1.45 | γ(SD:4.52) |
| LEV | 1.1 | 1.07–1.13 | γ(SD:0.16) |
| Antibiotics systemics | 1.21 | 1.11–1.30 | γ(SD:0.49) |
| Systemic o Inhaled Corticosteroids | 0.08 | 0.0–0.90 | γ(SD:4.18) |
| Bronchodilators | 0.04 | 0.03–0.04 | γ(SD:0.02) |
| Other drugs | 0.65 | 0.60–0.68 | γ(SD:0.04) |
| Medical devices | 10.24 | 9.71–10.76 | γ(SD:2.66) |
| Indirect cost patient-day | 17.24 | 16.38–18.07 | γ(SD:4.30) |