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. 2021 Jun 2;21:662. doi: 10.1186/s12885-021-08404-4

Table 2.

IC50 values of compounds 9, 10 and 11 and lawsone against C6, B16-F10 and A549

Compounds Cells
C6 B16F10 A549
CI50 (μM) CI50 (μM) CI50 (μM)
9 14.7 (10.3–21.4) 5.3 (4.8–5.8) 8.5 (7.6–9.5)
10 24.0 (16.5–80.1) 2.2 (1.0–4.0) 10.6 (6.9–18.1)
11 ND 15.7 (10.6–29.5) 21.2 (15.6–38.5)
Lawsone 26.8 (17.1–40.0) ND > 50

Values expressed as mean and 95% confidence interval of at least three independent experiments after treatment with synthetic derivatives of lawsone and lawsone for 72 h. ND - not determined