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. 2021 Jun 2;19:237. doi: 10.1186/s12967-021-02890-7

Fig. 5.

Fig. 5

Tissue remodeling-associated factors in WT mice after IL-24 treatment. The protein level of fibronectin (FN1) (a, d), pro-collagen type I alpha 2 (pro-COL1A2) (b, d) and αSMA (c, d) and mRNA expression of Tgfb1 (e), Pdgfb (f), Col1a1 (g), Col3a1 (h), Fn1 (i), Acta2 (j), Mmp2 (k), Mmp9 (l), Timp1 (m) and Timp2 (n) were determined by Western blot analysis and real-time PCR by comparison with GAPDH as internal control (n = 6). Results are presented as mean ± SD. *p < 0.05 vs. WT control (Mann–Whitney U-test)