Table 3.
Peri-operative analgesia in patients receiving opioid-free anaesthesia (OFA) and opioid-based anaesthesia (OBA)
| All patients (n = 80) | OFA (n = 40) | OBA (n = 40) | P-value | |
|---|---|---|---|---|
| Intraoperative analgesia | ||||
| Paracetamol | 79 (99) | 39 (98) | 40 (100) | > 0.99 |
| Nefopam | 72 (90) | 38 (95) | 34 (85) | 0.26 |
| Ketoprofen | 44 (55) | 32 (80) | 12 (30) | < 0.01 |
| Tramadol | 2 (3) | 2 (5) | 0 (0) | 0.49 |
| Morphine | 33 (41) | 1 (3) | 32 (80) | < 0.01 |
| Ketamine, n (%) | 76 (95) | 40 (100) | 36 (90) | 0.12 |
| Ketamine dose, mg | 75 [50–100] | 90 [75–100] | 50 [30–70] | < 0.001 |
| Lidocaine, n (%) | 50 (63) | 40 (100) | 10 (25) | < 0.01 |
| MgSO42− | 48 (60) | 40 (100) | 8 (20) | < 0.01 |
| Morphine titration | 51 (64) | 23 (58) | 28 (70) | 0.24 |
| Rescue analgesia during first 48 h | ||||
| Ketoprofen use | 30 (38) | 18 (45) | 12 (30) | 0.17 |
| Ketoprofen dose, mg | 100 [50–150] | 100 [75–200] | 100 [50–100] | 0.18 |
| Tramadol use | 7 (9) | 5 (13) | 2 (5) | 0.43 |
| Tramadol dose, mg | 200 [125–425] | 200 [100–400] | 325 [125–425] | 0.57 |
| Oxycodone oral | 23 (29) | 9 (23) | 14 (35) | 0.22 |
| Ketamine use | 8 (10) | 2 (5) | 6 (15) | 0.26 |
Data are presented as median [Interquartile range] or number (%) of patients. P value refers to comparison between OFA and OBA groups