Figure 3. Empagliflozin treatment improved mice exercise capacity after 6‐week TAC.
(A) Running time and (B) maximum oxygen uptake were measured in different groups. (C) Respiratory exchange ratio curves from 4 groups. (D) Blood lactate level at resting status and exhaustion in different groups; 2‐way ANOVA (repeated measures). Results are expressed as mean±SEM, n=5–6 in each group. RER indicates respiratory exchange ratio; and TAC, transverse aortic constriction. *P<0.05 vs sham, † P<0.05 vs TAC. One‐way ANOVA (non‐repeated measures) (A–C).