Table 1.
Baseline Characteristics of Patients With TAVR
| Overall | SR/SR | SR/AF | AF/AF | P Value, All Groups | P Value, SR/AF vs AF/AF | P Value, SR/AF vs SR/SR | P Value, SR/SR vs AF/AF | |
|---|---|---|---|---|---|---|---|---|
| No. | 1867 | 1478 | 60 | 329 | … | … | … | … |
| Age, y (SD) | 81.7 (6.6) | 81.5 (6.7) | 83.0 (6.6) | 82.4 (6.3) | 0.03 | 0.47 | 0.09 | 0.03 |
| % Male | 58.0% | 55.3% | 61.7% | 69.6% | <0.0001 | 0.22 | 0.33 | <0.0001 |
| % White | 94.4% | 93.8% | 89.7% | 97.5% | 0.009 | 0.003 | 0.20 | 0.008 |
| Body mass index, kg/m2 (SD) | 28.7 (6.2) | 28.8 (6.3) | 27.3 (5.0) | 28.6 (5.9) | 0.17 | 0.09 | 0.06 | 0.69 |
| Cardiovascular comorbidity | ||||||||
| Diabetes mellitus | 36.0% | 36.7% | 33.3% | 33.7% | 0.55 | 0.95 | 0.60 | 0.32 |
| Hypertension | 93.0% | 93.0% | 96.7% | 92.7% | 0.53 | 0.26 | 0.27 | 0.87 |
| Hyperlipidemia | 81.6% | 81.9% | 88.3% | 78.7% | 0.15 | 0.09 | 0.20 | 0.18 |
| Smoking (previous or current tobacco use) | 49.9% | 48.4% | 53.3% | 55.9% | 0.04 | 0.71 | 0.45 | 0.01 |
| Prior myocardial infarction | 16.7% | 16.5% | 28.3% | 15.2% | 0.04 | 0.01 | 0.02 | 0.56 |
| Prior coronary artery bypass graft | 25.9% | 26.4% | 23.3% | 24.3% | 0.66 | 0.87 | 0.60 | 0.44 |
| Prior heart failure | 84.6% | 84.1% | 90.0% | 85.7% | 0.38 | 0.37 | 0.22 | 0.47 |
| Prior stroke/transient ischemic attack | 17.0% | 16.2% | 10.0% | 21.9% | 0.02 | 0.03 | 0.20 | 0.01 |
| NYHA symptoms | ||||||||
| NYHA I | 0.1% | 0.1% | 0.0% | 0.0% | 0.88 | N/A | 0.84 | 0.64 |
| NYHA II | 25.2% | 26.2% | 18.3% | 22.2% | 0.15 | 0.50 | 0.17 | 0.13 |
| NYHA III | 60.4% | 59.7% | 66.7% | 62.3% | 0.40 | 0.52 | 0.28 | 0.38 |
| NYHA IV | 14.4% | 14.1% | 15.0% | 15.5% | 0.79 | 0.92 | 0.84 | 0.50 |
| Society of Thoracic Surgeons, renal disease defined by serum creatinine ≥2 mg/dL Score | 5.5 (1.7) | 5.5 (1.7) | 6.2 (2.2) | 5.8 (1.8) | <0.0001 | 0.11 | 0.0006 | 0.0007 |
| Congestive heart failure, hypertension, age, diabetes, previous stroke/transient ischemic attack, vascular disease, and sex category | 5.5 (1.2) | 5.5 (1.2) | 5.5 (1.0) | 5.5 (1.2) | 0.91 | 0.73 | 0.67 | 0.91 |
| Renal disease | 6.1% | 5.7% | 8.3% | 7.3% | 0.41 | 0.78 | 0.39 | 0.26 |
| Liver disease | 1.4% | 1.2% | 1.7% | 2.1% | 0.44 | 0.82 | 0.76 | 0.20 |
| Chronic obstructive pulmonary disease | 30.6% | 29.9% | 30.0% | 33.5% | 0.44 | 0.59 | 0.99 | 0.20 |
All values presented as means with SD in parentheses, or percentages. AF/AF indicates baseline AF/discharge AF; NYHA, New York Heart Association; SR/AF, baseline SR/discharge AF; SR/SR, baseline sinus rhythm/discharge sinus rhythm; and TAVR, thoracic aortic valve replacement..