Table 6.
All‐Cause Mortality: Multivariable Analysis
| Timepoint | Variable | TAVR | SAVR | ||
|---|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | ||
| 30 d | SR/AF vs SR/SR | 3.86 (0.44–34.28) | 0.22 | 3.34 (0.60–18.50) | 0.17 |
| AF/AF vs SR/SR | 1.60 (0.28–9.08) | 0.60 | 2.23 (0.29–16.99) | 0.44 | |
| STS risk score >8 | 1.02 (0.13–7.93) | 0.98 | 2.01 (0.42–9.70) | 0.38 | |
| Cardiomyopathy | 2.58 (0.72–9.27) | 0.15 | 4.11 (1.20–14.06) | 0.02 | |
| NYHA III/IV symptoms | 0.68 (0.23–1.98) | 0.48 | 0.86 (0.22–3.27) | 0.82 | |
| Previous MI | 1.55 (0.49–4.86) | 0.45 | 0.80 (0.17–3.77) | 0.78 | |
| Previous stroke/TIA | 0.72 (0.16–3.20) | 0.66 | 2.30 (0.67–7.90) | 0.19 | |
| 1 y | SR/AF vs SR/SR | 2.79 (1.37–5.68) | 0.005 | 2.19 (1.21–3.97) | 0.010 |
| AF/AF vs SR/SR | 2.13 (1.22–3.72) | 0.008 | 3.17 (1.62–6.21) | 0.0007 | |
| STS risk score >8 | 1.88 (1.14–3.10) | 0.01 | 1.76 (1.02–3.04) | 0.04 | |
| Cardiomyopathy | 1.06 (0.61–1.84) | 0.84 | 1.23 (0.67–2.27) | 0.50 | |
| NYHA III/IV symptoms | 0.87 (0.60–1.25) | 0.45 | 0.92 (0.57–1.50) | 0.74 | |
| Previous MI | 1.64 (1.13–2.37) | 0.009 | 1.47 (0.91–2.36) | 0.11 | |
| Previous stroke/TIA | 1.29 (0.87–1.91) | 0.21 | 1.06 (0.61–1.82) | 0.84 | |
| 2 y | SR/AF vs SR/SR | 3.23 (1.91–5.45) | <0.0001 | 2.28 (1.42–3.66) | 0.0007 |
| AF/AF vs SR/SR | 2.30 (1.53–3.47) | <0.0001 | 2.39 (1.33–4.31) | 0.004 | |
| STS risk score >8 | 1.64 (1.10–2.43) | 0.02 | 1.48 (0.93–2.37) | 0.10 | |
| Cardiomyopathy | 1.16 (0.78–1.73) | 0.47 | 1.37 (0.85–2.21) | 0.20 | |
| NYHA III/IV symptoms | 1.02 (0.76–1.36) | 0.90 | 0.96 (0.65–1.42) | 0.83 | |
| Previous MI | 1.48 (1.11–1.96) | 0.008 | 1.48 (1.00–2.18) | 0.050 | |
| Previous stroke/TIA | 1.37 (1.02–1.84) | 0.03 | 1.22 (0.80–1.86) | 0.37 | |
AF/AF indicates baseline AF/discharge AF; HR, hazard ratio; MI, myocardial infarction; NYHA, New York Heart Association; SAVR, surgical aortic valve replacement; SR/AF, baseline SR/discharge AF; SR/SR, baseline sinus rhythm/discharge sinus rhythm; STS, Society of Thoracic Surgeons; TAVR, transcatheter aortic valve replacement; and TIA, transient ischemic attack.