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. 2021 Mar 28;10(7):e018905. doi: 10.1161/JAHA.120.018905

Figure 3. Macrophage infiltration in fat pads.

Figure 3

A, Representative immunohistological staining, including cluster of differentiation (CD) 68 (a marker of macrophages), CD11c (a marker of M1 macrophages), and CD206 (a marker of M2 macrophages), of perivascular adipose tissue surrounding the saphenous vein (SV‐PVAT), that surrounding the internal thoracic artery (ITA‐PVAT), that surrounding the coronary artery (CA‐PVAT), and that surrounding the aorta (Ao‐PVAT). Bar=100 µm. B through D, Positive areas of immunohistological staining of CD68, CD11c, and CD206 in SV‐PVAT, ITA‐PVAT, CA‐PVAT, and Ao‐PVAT of patients (n=28). E, Ratios of the macrophage infiltration areas of CD11c/CD206 in SV‐PVAT, ITA‐PVAT, CA‐PVAT, and Ao‐PVAT. Results are shown as means±SD. *P<0.05 vs SV‐PVAT, P<0.05 vs ITA‐PVAT, P<0.05 vs CA‐PVAT.