Table 3.

TI Score Quintile Groups and the Risk of Recurrent Stroke

	Quintile Groups of TI Score
	G1	G2	G3	G4	G5
Number of cases	248	560	529	1209	387
TI score (mean±SD and range)	−0.78±0.17 [−1 to −0.5)	−0.41±0.08 [−0.5 to −0.25)	−0.17±0.06 [−0.25 to 0)	0	0.24±0.15 (0–1]
Crude model	13.50 [6.04 to 30.15]	4.51 [1.98 to 10.26]	Reference	5.80 [2.67–12.62]	1.70 [0.63–4.61]
Multivariable model #1	13.95 [6.24 to 31.16]	4.48 [1.97 to 10.20]	Reference	5.97 [2.74–13.01]	1.72 [0.64–4.67]
Multivariable model #2	13.43 [5.95 to 30.35]	4.59 [2.01 to 10.46]	Reference	6.60 [3.02–14.45]	1.68 [0.62–4.56]

Hazard ratios and 95% CIs were calculated using frailty models that considered the clustering effect of the treating hospitals. Multivariable model #1 was adjusted for age, sex, and baseline National Institutes of Health Stroke Scale score. Multivariable model #2 was adjusted for age, sex, baseline National Institutes of Health Stroke Scale score, stroke mechanism, hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and prestroke disability. TI indicates treatment intensification.