Table 1.
Characteristics of All Participants in Cohort 2 in Total and Based on Tertiles of Percent Prebeta‐1 HDL
| All Participants, n=1249 | Prebeta‐1 HDL Tertiles | P Value | |||
|---|---|---|---|---|---|
| <4.06%, n=416 | 4.06% to 9.18%, n=416 | >9.18%, n=417 | |||
| Age, y | 51.3±14.4 | 51.7±14.7 | 51.9±14.6 | 50.4±13.7 | 0.244 |
| Sex, % men | 42.4 | 32.5 | 43.3 | 51.3 | <0.001 |
| BMI, kg/m2 | 26.6±5.3 | 25.2±4.5 | 26.4±5.1 | 28.0±5.8 | <0.001 |
| Race/ethnicity % | |||||
| White | 78.5 | 76.4 | 77.9 | 81.3 | 0.215 |
| East Asian | 7.7 | 9.9 | 7.2 | 6.0 | 0.102 |
| Hispanic | 6.0 | 4.1 | 7.7 | 6.2 | 0.088 |
| Black | 4.0 | 4.6 | 4.1 | 3.4 | 0.669 |
| Mixed, other* | 3.7 | 5.0 | 2.9 | 3.1 | 0.191 |
| CHD, % | 27.9 | 20.0 | 29.3 | 34.3 | <0.001 |
| MI, % | 12.1 | 7.7 | 12.7 | 15.8 | 0.001 |
| Diabetes mellitus, % | 12.6 | 7.9 | 12.0 | 17.7 | <0.001 |
| Hypertension, % | 30.8 | 26.6 | 30.8 | 35.0 | 0.031 |
| Smoker (current), % | 7.8 | 6.8 | 8.9 | 7.7 | 0.516 |
| Triglycerides, mg/dL | 135 (56) | 105 (36) | 130 (41) | 197 (80) | <0.001 |
| LDL cholesterol, mg/dL | 154±62 | 147±55 | 153±54 | 161±73 | 0.021 |
| HDL cholesterol, mg/dL | 51.8±19.8 | 60.3±21.3 | 52.0±17.4 | 43.2±16.8 | <0.001 |
| Apolipoprotein AI, mg/dL | 126±37 | 127±38 | 128±39 | 123±35 | 0.137 |
| Lipid‐lowering medication, % | 18.2 | 12.0 | 19.5 | 23.0 | <0.001 |
For continuous variables, differences between the tertile groups were tested by ANOVA and for categorical variables by χ2 test. Prior to testing, skewed variables (triglycerides, LDL cholesterol, HDL cholesterol, and BMI) were log transformed. Data are presented as number of individual participants (percentage), mean±SD, or median (median absolute deviation). BMI indicates body mass index; CHD, coronary heart disease; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; and MI, myocardial infarction.
*
Other indicates Native American, North Asian, and South Asian.