Table 7.
Comparison of Prebeta‐1 HDL Levels According to Sex and Presence of Metabolic Syndrome Characteristics
| Trait (n) | Percent Prebeta‐1 HDL (SD) | P Value | Absolute Prebeta‐1 HDL, mg/dL (SD) | Percent Increase | P Value |
|---|---|---|---|---|---|
| Men (1088) | 8.96 (7.46) | <0.001 | 9.50 (8.36) | — | 0.862 |
| Women (1419) | 7.36 (6.34) | 9.66 (8.76) | |||
| Diabetic (263) | 9.82 (7.65) | <0.001 | 11.07 (8.69) | 17.5 | 0.005 |
| Nondiabetic (2244) | 7.85 (6.77) | 9.42 (8.56) | |||
| Low HDL* (996) | 10.18 (7.55) | <0.001 | 10.80 (8.80) | 22.9 | <0.001 |
| High HDL (1489) | 6.64 (6.05) | 8.79 (8.37) | |||
| High triglycerides † (1147) | 10.20 (7.55) | <0.001 | 11.96 (9.68) | 57.8 | <0.001 |
| Low triglycerides (1348) | 6.24 (5.70) | 7.58 (6.93) | |||
| Obese ‡ (512) | 10.10 (8.14) | <0.001 | 11.43 (10.38) | 24.2 | <0.001 |
| Nonobese (1942) | 7.60 (6.48) | 9.20 (8.04) | |||
| Hypertensive (810) | 8.52 (6.58) | 0.005 | 10.44 (8.45) | 13.6 | <0.001 |
| Normotensive (1695) | 7.84 (7.03) | 9.19 (8.63) |
Data are presented for the 2 combined cohorts with the number of individual participants in each instance and mean±SD. Percent prebeta‐1 HDL is defined as the percent of total plasma apolipoprotein AI present in prebeta‐1 HDL. The absolute level is the amount of apolipoprotein AI present in prebeta‐1 HDL expressed as milligrams per deciliter. HDL indicates high‐density lipoprotein.
*
Low HDL is defined as <40 mg/dL for men and <50 mg/dL for women.
†
High triglycerides are defined as ≥150 mg/dL.
‡
Obesity is defined as a body mass index >30 kg/m2.