Table 2.
Cox Hazard Analysis of HF‐Related Events in Patients With NIHF
| Variables | Cording | Univariate | Multivariable | ||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | ||
| Age | Per 1 y | 0.995 | 0.971–1.018 | 0.649 | … | ||
| Sex | Male (vs female) | 0.661 | 0.347–1.261 | 0.209 | … | ||
| Body mass index | Per 1 kg/m2 | 1.089 | 1.023–1.159 | 0.008 | Not selected | ||
| Hypertension | Yes (vs no) | 0.714 | 0.373–1.369 | 0.311 | … | ||
| Diabetes mellitus | Yes (vs no) | 1.013 | 0.490–2.092 | 0.973 | … | ||
| Dyslipidemia | Yes (vs no) | 0.877 | 0.460–1.671 | 0.689 | … | ||
| History of smoking | Yes (vs no) | 0.824 | 0.430–1.579 | 0.559 | … | ||
| Chronic kidney disease | Yes (vs no) | 1.059 | 0.549–2.042 | 0.864 | … | ||
| DROM | Per 1 U.CARR | 1.008 | 1.005–1.012 | <0.001 | 1.004 | 1.000–1.008 | 0.030 |
| BNP | Per 1 ln‐BNP | 2.452 | 1.703–3.531 | <0.001 | … | ||
| Hemoglobin | Per 1 g/dL | 0.799 | 0.684–0.933 | 0.005 | Not selected | ||
| Hs‐CRP | Per 1 ln‐hs‐CRP | 1.694 | 1.342–2.140 | <0.001 | … | ||
| Hs‐troponinT | Per 1 ln‐hs‐troponinT | 2.097 | 1.609–2.733 | <0.001 | 2.336 | 1.646–3.313 | <0.001 |
| Serum sodium | Per 1 mEq/L | 0.871 | 0.784–0.967 | 0.010 | Not selected | ||
| LVEF | Per 1 % | 0.985 | 0.964–1.005 | 0.143 | … | ||
| LVDd | Per 1 mm | 1.027 | 0.996–1.059 | 0.092 | … | ||
| LAD | Per 1 mm | 1.062 | 1.014–1.112 | 0.011 | 1.058 | 1.009–1.109 | 0.019 |
| E/e′ | Per 1 | 1.035 | 1.007–1.062 | 0.012 | Not selected | ||
BNP indicates B‐type natriuretic peptide; DROM, derivatives of reactive oxidative metabolites; E/e′, the ratio of early transmitral flow velocity to tissue Doppler early diastolic mitral annular velocity; HF, heart failure; Hs‐CRP, high‐sensitivity C‐reactive protein; Hs‐troponinT, high‐sensitivity troponin T; LAD, left atrial diameter; LVDd, left ventricular end‐diastolic dimension; LVEF, left ventricular ejection fraction; NIHF, nonischemic heart failure; and OR, odds ratio.