Table 1.

The neuroprotective effects of helium

	Experimental subject	Conclusion
Neonatal cerebral hypoxic ischemia	Rat	Helium preconditioning reduces infarct area, protects neurons and reduces nerve defects in rats at the early stage of hypoxic-ischemic injury
Traumatic brain injury	Mouse	Helium can effectively reduce cell death after injury.
Middle cerebral artery obstruction	Rat	Inhaling the mixture gas of helium and oxygen can reduce the infarct area and effectively reduce the neurological deficit
Oxygen-glucose deprivation	Neuron	Compared with the nitrogen group, the cell damage was more severe in the helium group during and after hypoxia