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. Author manuscript; available in PMC: 2021 Nov 10.
Published in final edited form as: J Am Coll Cardiol. 2020 Nov 10;76(19):2267–2281. doi: 10.1016/j.jacc.2020.08.079

TABLE 6.

The Importance of Inpatient and Outpatient CO Training Experience

Outpatient training
CV risk assessment and mitigation strategies before cancer therapy Anticipation for high-risk cancer treatment
  • Perform a comprehensive baseline CV risk and disease assessment

  • Review medication- and patient-related risks for negative effects on cardiac function, the vascular system, arrhythmias including drug-drug interactions and QTc prolongation

  • Individualize preventive strategies as well as type and timing of follow-up based on expected CV risk profile and disease burden

Optimization of pre-existing CVD
  • Assess for the presence, type and extent of CVDs as well as prior and current management of these

  • Determine repeat evaluation and optimization

  • Anticipate impact of pre-existing CVD on cancer therapy and vice versa

Evaluation and management of common CVDs in cancer patients on active therapy (pre-existing and newly arising) Left ventricular dysfunction
  • Evaluate the contribution from cancer treatment and guide ongoing treatment in collaboration with the oncologist

  • Institute appropriate HF guideline-directed medical therapy

CAD
  • Determine when and how to work up and treat CAD in this population

PAD
  • Assess whether cancer treatment is contributing to PAD

VTE and PE
  • Identify patients at risk of VTE and PE, and provide therapeutic recommendations to minimize such risk

  • Guide need for anticoagulation and medical management

Arrhythmias
  • Assess whether current cancer treatment is contributing to arrhythmia burden

  • Guide need for anticoagulation and medical management

  • Recognize potential drug-drug interactions between anti-arrhythmic drugs and chemotherapy, targeted therapy and immunotherapy

Cardiac masses
  • Contribute to the diagnostic work-up and the management of patients with cardiac masses

Survivorship
  • Understand long-term CV and oncological risk in survivors of cancer

  • Provide aggressive CV risk factor reduction in this population

  • Plan appropriate cardiac follow-up/monitoring based on the specific risk of the patient

Inpatient training
Evaluation and management of cardio-oncological emergencies Cardiac tamponade
  • Appraise the risks/benefits of emergent pericardiocentesis in critically ill patients, including those with hematologic complications (e.g., thrombocytopenia)

SVC syndrome
  • Provide recommendations for the management of symptomatic SVC syndrome including endovenous recanalization, surgery, and/or thrombolysis

ACS
  • Select the best treatment option in patients presenting with ACS and malignancy

Cardiac arrhythmias
  • Diagnose and manage hemodynamically significant arrhythmias

  • Recognize potential drug-drug interactions between anti-arrhythmic drugs and chemotherapy/targeted therapy/immunotherapy

VTE and PE
  • Identify patients at risk of VTE and PE, and provide therapeutic recommendations to minimize such risk

  • Guide need for anticoagulation and medical management

Acute heart failure
  • Recognize potential causes of acute heart failure in the oncology patient

  • Apply evidence-based strategies in the diagnosis and treatment of acute heart failure

Myocarditis
  • Diagnose and manage myocarditis due to cancer therapy

Cardiac masses
  • Diagnose and contribute to the management of patients with primary or metastatic cardiac masses

Evaluation and management of bone marrow transplant patients
  • Provide cardiovascular risk stratification for candidates in which bone marrow transplantation is planned, including potential drug-drug interactions

  • Recognize and manage cardiovascular complications due to acute and chronic graft-versus-host disease

Evaluation and management of the oncology patient in the intensive care unit
  • Provide expert recommendations on the cardiovascular care of the critically ill oncology patient

  • Demonstrate proficiency in the management of cardiogenic shock in the oncology patient considering a patient’s cancer diagnosis, treatment, and prognosis

ACS = acute coronary syndrome; CAD = coronary arterydisease; PAD = peripheral arterialdisease; PE = pulmonary embolism; SVC = superior vena cava; VTE = venous thromboembolism; other abbreviations as in Table 1.