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In vitro antifungal activity of ganetespib used alone or in combination with FLC against azole-resistant clinically isolated strains.
| Strains |
MIC80
(μg/mL) |
FICFLC
(μg/mL) |
FICcompd
(μg/mL) |
FICI |
|---|---|---|---|---|
| C. tropicalis 5008 | >64 | 0.5 | 2 | 0.039 |
| C. albicans 7781 | >64 | 0.25 | 2 | 0.035 |
| C. auris 0029 | >64 | 32 | 64 | 1.500 |
| C. glabrata 9703 | >64 | 16 | 8 | 1.125 |
