Table 2. Qualitative/Categorical traits with three or more categories that are differentially distributed between at least one of the adipose and brain-specific subtype groups of individuals for BMI and the remaining population.
For each trait, we provide the p-values of testing heterogeneity between each tissue-specific subtype group of individuals and the remaining population before (primary) and after BMI adjustment (BMIadj). For each trait, tissue-specific groups which appear to be significantly heterogeneous (signif tissue) before (primary) and after BMI adjustment (BMIadj) are also provided. The asterisk mark attached to the traits indicate which trait remains differentially distributed between at least one of the tissue-specific groups and the remaining population after BMI adjustment. The number of categories for each trait (#categ) are also listed.
| Trait | P adipose | P brain | signif tissue | #categ | |||
|---|---|---|---|---|---|---|---|
| primary | BMIadj | primary | BMIadj | primary | BMIadj | ||
| *Overall health rating | 4.98E-239 | 1.83E-15 | 6.96E-87 | 1.59E-19 | both | both | 4 |
| *Alcohol intake frequency | 8.05E-133 | 1.51E-06 | 7.47E-73 | 3.09E-11 | both | both | 6 |
| *Frequency of tiredness lethargy in last weeks | 4.04E-91 | 0.63 | 4.03E-38 | 9.44E-06 | both | brain | 4 |
| *Frequency of depressed mood in last 2 weeks | 5.00E-50 | 2.41E-05 | 3.09E-27 | 5.23E-07 | both | both | 4 |
| *Frequency of unenthusiasm disinterest in last 2 weeks | 3.41E-47 | 5.74E-05 | 3.26E-22 | 0.005 | both | adipose | 4 |
| *Falls in the last year | 5.19E-45 | 6.42E-05 | 3.72E-15 | 0.0002 | both | both | 3 |
| Illness injury bereavement stress in last 2 years | 6.49E-44 | 0.5 | 1.11E-10 | 0.93 | both | none | 7 |
| *Alcohol drinker status | 2.50E-35 | 7.56E-18 | 1.66E-29 | 2.17E-24 | both | both | 3 |
| Getting up in morning | 1.05E-28 | 0.14 | 2.20E-23 | 0.003 | both | none | 4 |
| *Weight change compared with 1 year ago | 6.15E-21 | 3.81E-13 | 9.43E-23 | 3.18E-20 | both | both | 3 |
| *Smoking status | 3.14E-06 | 1.31E-08 | 7.62E-24 | 3.06E-11 | both | both | 3 |
| *Sleeplessness insomnia | 7.15E-24 | 5.09E-05 | 2.88E-10 | 0.0001 | both | both | 3 |
| Frequency of tenseness restlessness in last 2 weeks | 5.08E-19 | 0.26 | 5.24E-20 | 0.004 | both | none | 4 |
| Daytime dozing sleeping narcolepsy | 1.51E-17 | 0.84 | 0.0002 | 0.4 | both | none | 4 |
| Blood clot DVT bronchitis emphysema asthma rhinitis eczema allergy diagnosed by doctor | 5.76E-19 | 0.05 | 1.36E-08 | 0.24 | both | none | 6 |
| *Current tobacco smoking | 5.16E-07 | 1.51E-08 | 4.88E-19 | 2.71E-11 | both | both | 3 |
| *Past tobacco smoking | 2.63E-06 | 3.81E-12 | 1.86E-15 | 2.47E-09 | both | both | 4 |
| Qualifications | 1.31E-08 | 0.30 | 1.62E-06 | 0.1 | both | none | 7 |
| Alcohol intake versus 10 years previously | 4.16E-21 | 0.11 | 0.005 | 0.36 | adipose | none | 3 |
| Nap during day | 1.30E-14 | 0.08 | 0.06 | 0.02 | adipose | none | 3 |
| Morning evening person chronotype | 2.88E-07 | 0.43 | 0.0007 | 0.72 | adipose | none | 4 |