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. 2021 Mar 1;320(5):F761–F771. doi: 10.1152/ajprenal.00552.2020

Figure 1.

Figure 1.

Effects of Na-glucose cotransporter (SGLT2) inhibitor on glomerular filtration rate (GFR), urine flow rate, and urine electrolyte excretion in diabetic rats fed high-NaCl or low-NaCl diets. The line graphs show values for individual animals. The bar graphs show group means ± SE for the effects of SGLT2 inhibitor. SGLT2 inhibitor reduced GFR and was diuretic and natriuretic (P < 0.001). P values in the bar graphs refer to the differential response to SGLT2 inhibitor between animals fed high-NaCl or low-NaCl diets. *P < 0.02 and **P < 0.001 for effect of SGLT2 blocker in animals on the designated diet.