fig 1.

Continued.

G and H, Further follow-up MR study, April 1999 (4 months after initiation of HAART). FLAIR-FSE (10000/150, TI = 2600) image (G) reveals regression of the white matter changes with partially present low signal (corresponding to areas of increased hypoattenuation on T1-weighted images). Note atrophic changes of the right hemisphere with widening of the ventricle (arrow). Further increase in hypointensity is evident on T1-weighted (550/20) image (H). Elongated hyperintense area is seen medial to the sylvian fissure, representing subacute hemorrhage (arrow). Enhancement was not present on contrast-enhanced T1-weighted image (not shown).

I and J, Follow-up MR examination, September 2000 (21 months after initiation of HAART). Axial FLAIR-FSE (7384/130, TI = 2100) image (I) and contrast-enhanced T1-weighted (8/2.7, flip angle = 10°) image (J) show atrophic changes in the right hemisphere with widening of the sulci and further ex-vacuo widening of the right ventricle (arrow). Note low signal on the FLAIR-FSE image, representing leukomalacia