Table 1.
Age, median years (IQR) | 35 (29-41) |
Race, n (%) | |
White | 150 (72.5) |
Asian | 13 (6.3) |
Black | 9 (4.4) |
Hispanic, n (%) | 52 (25.1) |
Body mass index (BMI), median kg/cm2 (IQR) | 36.4 (31.8-41.2) |
Obesity (BMI ≥ 30 kg/cm2), n (%) | 167 (80.7) |
Waist circumference, median cm (IQR) | 112 (99-120) |
Abdominal adiposity (waist > 88cm), n (%) | 192 (92.8) |
Hypertension, n (%) | 65 (31.4) |
Total cholesterol, median mg/dL (IQR) | 190 (167-215) |
HDL, median mg/dL (IQR) | 42 (35-50) |
LDL, median mg/dL (IQR) | 117 (94-138) |
Triglycerides, median mg/dL (IQR) | 146 (115-196) |
Dyslipidemia | 198 (95.7) |
Type 2 diabetes, n (%) | 67 (32.4) |
HOMA-IR, median mg/dL (IQR) | 4.6 (2.8-8.0) |
Polycystic ovary syndrome (PCOS), self-report, n (%) | 43 (20.8) |
Total testosterone, median pg/mL (IQR) | 210 (120-290) |
Free testosterone (Free T), median pg/mL (IQR)* | 2.8 (1.6-4.8) |
Sex hormone binding globulin, median nmol/L (IQR) | 37.8 (24.9-62.9) |
NASH (borderline or definite), n (%) | 144 (69.6) |
NAFLD Activity Score, median (IQR) | 4 (3-6) |
NAFLD Activity Score among those with NASH | 5 (4-7) |
Any fibrosis, n (%) | 140 (67.6) |
Any fibrosis among those with NASH | 131 (91.0) |
Advanced fibrosis (stages 3-4), n (%) | 31 (15.0) |
Advanced fibrosis among those with NASH | 30 (20.8) |
Normal range for pre-menopausal populations 0.6-9.8pg/mL17