. Author manuscript; available in PMC: 2022 Jun 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2020 Oct 1;19(6):1267–1274.e1. doi: 10.1016/j.cgh.2020.09.045

Table 2.

Free Testosterone is Associated With NASH and NASH Fibrosis in Younger Pre-Menopausal Women with NAFLD (n=207)

NAFLD Comparisons	1^st Age Quartile n=52 Median 25 years (IQR 22-27)	2^nd Age Quartile n=52 Median 32 years (IQR 31-34)	3^rd Age Quartile n=52 Median 39 years (IQR 37-40)	4^th Age Quartile n=51 Median 47 years (IQR 44-50)
NAFLD Comparisons	Adjusted OR (95% CI), p-value
NASH (vs NAFL)	2.28 (1.18-4.39) p=0.013	0.95 (0.55-1.61) p=0.836	0.88 (0.45-1.71) p=0.700	0.82 (0.44-1.52) p=0.520
Any fibrosis (vs none)	2.08 (1.13-3.82) p=0.018	0.78 (0.47-1.30) p=0.350	0.81 (0.43-1.51) p=0.502	0.78 (0.40-1.51) p=0.448
Higher fibrosis stage (from stages 0-4)	1.94 (1.12-3.38) p=0.019	0.72 (0.47-1.11) p=0.137	0.67 (0.41-1.08) p=0.101	0.84 (0.50-1.41) p=0.523

Adjusted for DM2, abdominal adiposity, and dyslipidemia. From lowest to highest age quartiles, NASH was present in n=34, n=37, n=39, and n=34 participants, and any fibrosis was present in n=32, n=34, n=37, and n=37 participants, respectively.