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. 2021 May 19;12:620740. doi: 10.3389/fgene.2021.620740

TABLE 4.

Chemicals associated with obesity and weight gain.

Num. Gene symbol Gene name Inference network Inference score
1 CD53 CD53 molecule Benzo(a)pyrene, bissulfone, bisphenol A, Cadmium Chloride, Carbon Tetrachloride, Choline, Cisplatin, Dexamethasone, Dietary Fats, Diethylstilbestrol, Ethinyl Estradiol, Lipopolysaccharides, Methionine, Parathion, Phenobarbital, Resveratrol, Sodium Selenite, Streptozocin, Tamoxifen, testosterone enanthate, tetrabromobisphenol A, Tetrachlorodibenzodioxin, Tretinoin 76.60
2 FCER1G Fc fragment of IgE receptor Ig Azoxymethane, Benzo(a)pyrene, bis(4-hydroxyphenyl)sulfone, bisphenol A, Carbon Tetrachloride, Choline, Cisplatin, Cyclophosphamide, Dexamethasone, Dietary Fats, Diethylhexyl Phthalate, Diethylstilbestrol, Estradiol, Ethinyl Estradiol, Lipopolysaccharides, Methionine, methylmercuric chloride, Plant Preparations, Probucol, Quercetin, Resveratrol, sodium arsenite, Streptozocin, testosterone enanthate, tetrabromobisphenol A, Tetrachlorodibenzodioxin, Tobacco Smoke Pollution, Tretinoin, Troglitazone, Valproic Acid 101.45
3 TYROBP TYRO protein tyrosine kinase binding protein Acrylamide, benzo(a)pyrene, bissulfone, bisphenol a, carbon tetrachloride, choline, cisplatin, curcumin, cyclophosphamide, dexamethasone, dietary fats, diethylstilbestrol, estradiol, ethinyl estradiol, genistein, lipopolysaccharides, methionine, oxygen, resveratrol, sodium arsenite, streptozocin, tetrachlorodibenzodioxin, tobacco smoke pollution, tretinoin, troglitazone, valproic acid 84.36
4 CTSS Cathepsin S Bissulfone, bisphenol a, chlorpyrifos, cholesterol, dietary, curcumin, cyclosporine, dietary fats, diethylnitrosamine, fenretinide, folic acid, pirinixic acid, polychlorinated biphenyls, resveratrol, streptozocin, tetrachlorodibenzodioxin, valproic acid 37.38
5 C1QC Complement C1q C chain 3,4,5,3′,4′-pentachlorobiphenyl, amitriptyline, azoxymethane, benzo(a)pyrene, bis(4-hydroxyphenyl)sulfone, bisphenol a, cadmium chloride, carbon tetrachloride, cisplatin, coenzyme q10, curcumin, cyclophosphamide, decabromobiphenyl ether, dexamethasone, dietary fats, diethylhexyl phthalate, diethylstilbestrol, estradiol, ethanol, ethinyl estradiol, genistein, lipopolysaccharides, lycopene, medroxyprogesterone acetate, nickel sulfate, oxygen, phenobarbital, resveratrol, sirolimus, streptozocin, tacrolimus, testosterone enanthate, tetrabromobisphenol a, tetrachlorodibenzodioxin, thioctic acid, tobacco smoke pollution, troglitazone, valproic acid 129.98
6 ITGB2 Integrin subunit beta 2 3,4,5,3′,4′-pentachlorobiphenyl, atorvastatin, azoxymethane, benzo(a)pyrene, bis(4-hydroxyphenyl)sulfone, bisphenol a, cadmium chloride, carbon tetrachloride, catechin, choline, cisplatin, decabromobiphenyl ether, dexamethasone, diazinon, dietary fats, environmental pollutants, estradiol, ethanol, ethinyl estradiol, lipopolysaccharides, lovastatin, methionine, probucol, quercetin, resveratrol, sodium arsenite, streptozocin, tetrabromobisphenol a, tetrachlorodibenzodioxin, tobacco smoke pollution, tretinoin, tributyltin, valproic acid 91.08
7 PLEK Pleckstrin Arsenic, azoxymethane, benzo(a)pyrene, bisphenol a, carbon tetrachloride, celecoxib, choline, cisplatin, dietary fats, ethanol, ethinyl estradiol, methionine, nickel sulfate, pioglitazone, plant extracts, quercetin, resveratrol, tetrabromobisphenol a, tetrachlorodibenzodioxin, Tobacco Smoke Pollution, Tretinoin 73.29