Table 2.
Sensitivity of the nucleoprotein (NP), RBD-based, and NP/RBD-based IgG ELISAs at a specificity of 98.3%
| Positive sera (%) | ||||
|---|---|---|---|---|
| Time post infection | No. of sera | NP | RBD | NP/RBD |
| > 4 weeks | 98 |
82.7 CI [73.74; 89.60] |
92.9 CI [85.89; 97.11] |
95.9 CI [89.85; 98.87] |
| 4–10 weeks | 48 |
95.8 CIa [85.70; 99.48] |
97.9 CI [88.9; 99.95] |
100.0 CI [92.60; 100.00] |
| 6 months | 50 |
70.0 CI [55.39; 82.14] |
88.0 CI [75.69; 95.47] |
92.0 CI [80.77; 97.78] |
| p-levelb | 0.0008* | 0.0585 | 0.0465* | |
aCI: 95% confidence interval
bComparison of the sensitivity 4–10 weeks versus 6 months post infection by the chi-squared test. Significant p-values are labeled with an asterisk