Table 5.
Summary of adverse events.
| Studies | Experimental | Control | Adverse events | |||
|---|---|---|---|---|---|---|
| n (Case) | Total | n (Case) | Total | Experimental | Control | |
| Chen 2019 [20] | 0 | 40 | 4 | 40 | Fatigue, drowsiness, and loss of memory | |
| Fu 2018 [23] | 4 | 27 | 9 | 26 | Lip numbness, consciously thickened lips, tongue numbness and discomfort in throat, and bitter mouth | Drowsiness during the day, dizziness and fatigue, dry mouth, and bitter mouth |
| Liu 2018 [26] | 0 | 30 | 2 | 30 | Constipation | |
| Zhang 2017 [29] | 4 | 28 | 5 | 24 | Dry mouth, disgusting | Dizziness, fatigue, upset, and loss of appetite |
| Zhang 2019 [32] | 2 | 29 | 2 | 28 | Acid reflux, heartburn, and loose stools | Dizzy |