Table 4.

Multivariate analysis of factors influencing liver function capacity 12 months after surgery

Operative procedure	Independent factors	Estimate, β	SE	95% Confidence interval	p-value
RYGB	Intercept	184.7	428.3	− 654.6–1024.1	0.666
	Sex	93.5	60.2	− 24.6–211.6	0.121
	T2DM	− 37.2	60.6	− 156.0–81.5	0.539
	Arterial hypertension	− 45.7	60.6	− 164.5–73.1	0.450
	Age	− 3.0	2.4	− 7.8–1.7	0.211
	Weight	− 3.1	1.5	− 6.2 to − 0.1	0.043*
	BMI	7.4	5.5	− 3.4–18.2	0.182
	LiMAx	0.4	0.2	0.1–0.7	0.007*
	APRI	− 262.3	717.7	− 1669.1–1144.4	0.715
	AST	− 1.4	3.6	− 8.4–5.6	0.699
	ALT	− 0.1	2.4	− 4.8–4.5	0.950
	GGT	− 1.1	1.0	− 3.1–1.0	0.301
	HbA1c	51.3	48.1	− 43.0–145.5	0.286
	%EBMIL 12 months after surgery	0.3	3.2	− 6.0–6.6	0.935
SG	Intercept	98.1	210.5	− 314.4–510.6	0.641
	Sex	− 140.3	51.4	− 241.0 to − 39.6	0.006*
	T2DM	− 6.5	38.0	− 80.8–67.9	0.864
	Arterial hypertension	− 1.4	40.0	− 79.9–77.1	0.972
	Age	3.5	2.1	− 0.740–7.7	0.106
	Weight	1.1	1.3	− 1.5–3.7	0.406
	BMI	1.3	3.0	− 4.5–7.1	0.659
	LiMAx	0.6	0.1	0.3–0.8	0.000*
	APRI	1241.8	395.0	467.6–2016.1	0.002*
	AST	− 1.4	2.8	− 6.9–4.187	0.632
	ALT	− 3.6	2.3	− 8.1–1.0	0.123
	GGT	1.1	0.8	− 4.4–2.6	0.165
	HbA1c	− 50.2	25.4	− 99.9 to − 0.4	0.049*
	%EBMIL 12 months after surgery	0.8	1.3	− 1.7–3.3	0.514

Abbreviations: BMI, body mass index; LiMAx, liver function capacity test; SG, sleeve gastrectomy; RYGB, Roux-en-Y-gastric bypass; SE standard error; T2DM type 2 diabetes mellitus; APRI, aspartate aminotransferase (AST) to platelet ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase; HbA1c, glycated hemoglobin; %EBMIL, percentage excess BMI loss; * statistically significant using generalized linear model