Skip to main content
. 2021 May 28;6(12):4816–4829. doi: 10.1016/j.bioactmat.2021.05.022

Fig. 6.

Fig. 6

Investigation on DRG growth. (A) and (B) were SEM images of Cur-loaded FC and FC/FI hydrogels, respectively. (C) Cur release curves from FC and FC/FI hydrogels. (D) Laser scanning confocal images of DRG spheres (green, NF200+) and SCs (red, S100+) cultured for 7 days on different hydrogels. (E) Neurite myelination after DRG cultivation for 30 days on different hydrogels. Cell nuclei were stained by DAPI in (D) and (E). (F) Statistical analysis of neurite length (a), number of SCs migrating away from DRG spheres as a function of migration distance (b) and the percentage of axon-attached SCs (c). DRG spheres were cultured for 7 days on different hydrogels. (G) Relative ERK2, AKT1 and MBP gene expressions on different hydrogels after culturing of DRG neurons for 30 days. *p < 0.05, **p < 0.01, and ***p < 0.001.