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editorial
. 2021 May 4;68(7):953–961. doi: 10.1007/s12630-021-01988-2

TABLE 2.

Proposed definitions related to death by neurologic criteria

Proposed actualized definition Conceptual model correlate
Flow Movement of blood detected by opacification of major brain* vessels (arteries and veins) in blood flow studies Is there water in the hose?
Perfusion Capillary-level flow in the target tissue (in this case brain, specifically brainstem) Is water reaching the plant?
Function Organized clinical brainstem neuronal function as manifest by consciousness and brainstem reflexes Is the flower alive?

*Brain is defined as the combination of the cerebrum and the brainstem.

Proposed actualized definitions of the concepts of brain blood flow, perfusion, and function in the light of our new conceptual model. These actualized definitions put the emphasis on the physiologic differences between the three concepts to avoid potential misinterpretation or misnaming.