Table 1.
Population characteristics.
| Clinical parameters | N = 37 |
|---|---|
| Age (years) | 31.1 ± 7.7 |
| BMI (kg/m2) | 22.4 ± 3.2 |
| Gender (M/F) | 14/23 |
| Ulcer (%) | 8.1% |
| ACS (%) | 77% |
| Retinopathy (%) | 24% |
| Priapism (% males) | 28.6% |
| Hydroxycarbamide (%) | 35.1% |
| Hemodynam ic parameters | |
| SBP (mmHg) | 111 ± 9.3 |
| DBP (mmHg) | 57 ± 7.0 |
| MAP (mmHg) | 75 ± 7.1 |
| HR (beats/min) | 73 ± 9.7 |
| PP (mmHg) | 53 ± 7.0 |
| PW V (m/s) | 8.0 ± 1.2 |
| CI (l/min/m2) | 4.6 ± 0.7 |
| LVMI (g/m2) | 110 ± 21.1 |
| TRV (m/s) | 2.50 ± 0.18 |
| SVR (dynes/s/cm−5) | 759 ± 151 |
| Biological parameters | |
| Creatinine (µmol/l) | 46.6 ± 12.3 |
| ACR (mg/mmol) | 47.8 ± 52.0 |
| Hb (g/dl) | 8.4 ± 1.1 |
| Reticulocyte (103/mm3) | 303 ± 141 |
| Bilirubin (UI/l) | 65 ± 42 |
| LDH (UI/l) | 478 ± 122 |
| ADMA (µmol/l) | 1.07 ± 0.45 |
| Fasting glucose (mmol/l) | 4.90 ± 0.43 |
| Fasting insulin (mUI/l) | 4.58 ± 2.7 |
BMI: body mass index; ACS: acute chest syndrome; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; HR: heart rate; PP: pulse pressure; PWV: pulse wave velocity; CI: cardiac index; LVMI: left ventricular mass index; TRV: tricuspid regurgitation velocity; SVR: systemic vascular resistance; ACR: albumin creatinine ratio; Hb: haemoglobin; LDH: lactic dehydrogenase; ADMA: asymetric dimethyl arginine.