Table 2.

KEGG pathway and Cellular processes analysis of Hub genes implicated in EOCRC progression on STRING database. (A) Cellular process analysis of Hub genes on string database. (B) KEGG pathway analysis of Hub genes on string database.

(A)	GO-term	Description	Count in gene set	False discovery rate
1	GO:0005899	Insulin receptor complex	2 of 2	0.00048
2	GO:0009986	Cell surface	6 of 690	0.00099
3	GO:0009897	External side of plasma membrane	4 of 223	0.00099
4	GO:0005887	Integral component of plasma membrane	8 of 1564	0.00099
5	GO:0098802	Plasma membrane receptor complex	3 of 158	0.0065

(B)	Pathway	Description	Count in gene set	False discovery rate
1	hsa04060	Cytokine–cytokine receptor interaction	7 of 263	1.23e−07
2	hsa04640	Hematopoietic cell lineage	5 of 94	7.12e−07
3	hsa04010	MAPK signaling pathway	6 of 293	3.50e−06
4	hsa04151	PI3K-Akt signaling pathway	5 of 348	0.00016
5	hsa04014	Ras signaling pathway	4 of 228	0.00036