Table 2:
Spearman r and P-value for correlations between structural abnormality scores from UTE MRI and functional measures from spirometry, MBW, and 129Xe MRI.
| FEV1 z-score | FEF25–75 z-score | FEV1/FVC z-score | LCI2.5 | VDP | |
|---|---|---|---|---|---|
| Total Brody Score | r = −0.31 | r = −0.35 | r = −0.44 | r = 0.47 | r = 0.41 |
| (P = 0.12) | (P = 0.07) | (P = 0.02) | (P = 0.01) | (P = 0.03*) | |
| Mucus Plugging | r = −0.23 | r = −0.33 | r = −0.45 | r = 0.51 | r = 0.53 |
| (P = 0.23) | (P = 0.10) | (P = 0.02) | (P < 0.01) | (P <0.01) | |
| Bronchial Wall Thickening | r = −0.16 | r = −0.17 | r = −0.27 | r = 0.39 | r = 0.32 |
| (P = 0.43) | (P = 0.40) | (P = 0.17) | (P =0.05*) | (P = 0.10) | |
| Bronchiectasis | r = −0.14 | r = −0.14 | r = −0.21 | r = 0.36 | r = 0.33 |
| (P = 0.50) | (P = 0.49) | (P = 0.30) | (P = 0.07) | (P = 0.09) | |
| Ground Glass | r = −0.44 | r = −0.47 | r = −0.30 | r = 0.09 | r = −0.00 |
| (P = 0.02) | (P = 0.01) | (P = 0.12) | (P = 0.66) | (P = 0.98) | |
| Consolidation/Atelectasis | r = −0.46 | r = −0.45 | r = −0.46 | r = 0.35 | r = 0.34 |
| (P = 0.02) | (P = 0.02) | (P = 0.02) | (P = 0.07) | (P = 0.08) | |
| Air Trapping | r = −0.10 | r = −0.19 | r = −0.27 | r = 0.28 | r = 0.12 |
| (P = 0.55) | (P = 0.33) | (P = 0.17) | (P = 0.16) | (P = 0.95) | |
| Cysts/Bullae | r = 0.09 | r = 0.16 | r = 0.18 | r = −0.03 | r = 0.01 |
| (P = 0.66) | (P = 0.41) | (P = 0.38) | (P = 0.90) | (P = 0.95) |
Statistically significant correlations are in bold.
*
indicates no longer significant after correction for multiple tests.