Liang YM 2017.
Study characteristics | ||
Methods | RCT, single centre, 60 participants, 1 year duration | |
Participants | 60 enrolled: CHM = 30, control = 30, 20 to 40 years, baseline was comparable 60 analysed/evaluated: CHM = 30, control = 30 PCOS DC: consistent with Rotterdam criteria (evaluated by review authors) In: PCOS and infertility Ex: using other drugs for ovulation induction, participants unable to follow‐up, tumour patients, adrenal diseases, non‐ovulatory infertility, other hyperandrogenic diseases |
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Interventions | CHM + CC versus CC CHM: bu shen huo xue decoction (day 5 of menstrual cycle, one dose per day, decocted in water, bid, 3 weeks), clomiphene (day 5 of menstrual cycle, 50 mg, once a day, 5 days) Control: clomiphene (day 5 of menstrual cycle, 50 mg, once a day, 5 days) Duration: 3 menstrual cycles (stop treatment when pregnancy was founded); follow‐up three months |
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Outcomes | Pregnancy rate Ovulation rate (per cycle) BMI, sex hormones, blood lipid |
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Notes | This is a dissertation. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Random number table |
Allocation concealment (selection bias) | Unclear risk | Failed to obtain this information from the author |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Failed to obtain this information from the author |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Failed to obtain this information from the author |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No withdrawal or dropout |
Selective reporting (reporting bias) | Unclear risk | The study protocol was unavailable |
Other bias | Low risk | No other potential risk of bias identified |