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. 2021 Jun 4;2021(6):CD007535. doi: 10.1002/14651858.CD007535.pub4

Liang YM 2017.

Study characteristics
Methods RCT, single centre, 60 participants, 1 year duration
Participants 60 enrolled: CHM = 30, control = 30, 20 to 40 years, baseline was comparable
60 analysed/evaluated: CHM = 30, control = 30
PCOS DC: consistent with Rotterdam criteria (evaluated by review authors)
In: PCOS and infertility
Ex: using other drugs for ovulation induction, participants unable to follow‐up, tumour patients, adrenal diseases, non‐ovulatory infertility, other hyperandrogenic diseases
Interventions CHM + CC versus CC
CHM: bu shen huo xue decoction (day 5 of menstrual cycle, one dose per day, decocted in water, bid, 3 weeks), clomiphene (day 5 of menstrual cycle, 50 mg, once a day, 5 days)
Control: clomiphene (day 5 of menstrual cycle, 50 mg, once a day, 5 days)
Duration: 3 menstrual cycles (stop treatment when pregnancy was founded); follow‐up three months
Outcomes Pregnancy rate
Ovulation rate (per cycle)
BMI, sex hormones, blood lipid
Notes This is a dissertation.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random number table
Allocation concealment (selection bias) Unclear risk Failed to obtain this information from the author
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Failed to obtain this information from the author
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Failed to obtain this information from the author
Incomplete outcome data (attrition bias)
All outcomes Low risk No withdrawal or dropout
Selective reporting (reporting bias) Unclear risk The study protocol was unavailable
Other bias Low risk No other potential risk of bias identified