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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Adv Healthc Mater. 2020 Dec 4;10(15):e2001169. doi: 10.1002/adhm.202001169

Figure 3: Computational fluid dynamics (CFD) modeling of hemodynamics in developing human heart constructs.

Figure 3:

(A) Conversion of an anatomical embryonic heart tube (e-HT, 84X) geometry into a meshed boundary for CFD analysis performed with anatomically appropriate flow wavefront (B). CFD results demonstrated the velocity and wall shear stress at peak flow (C). D-F: Conversion of a patient-specific 3D printed fetal left ventricle (f-LV, 1X scale) geometry into a meshed boundary for CFD analysis (D) performed using an anatomically appropriate flow wavefront (E). CFD results demonstrated velocity and wall shear stress at peak flow (F). The inset in (F – right panel) shows zoomed in views of peak wall shear stress with higher values at the aortic outflow tract.