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. 2021 Jun 3;11:11707. doi: 10.1038/s41598-021-91070-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of high concentrations of cobalt, copper and magnesium ions on THP-1 cell morphology. Elongated cells, which were defined as those in which the aspect ratio was higher than 2.5, are indicated with black arrows. Scale bars = 100 μm.