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. 2021 Jun 3;4:672. doi: 10.1038/s42003-021-02225-8

Fig. 7. PAG depletion in T cells is sufficient for an anti-tumor effect.

Fig. 7

MC38 tumors were implanted in WT mice that received two adoptive transfers of 8.5 × 106 WT or KO CD3+ T cells (six mice per group). a, b Daily tumor growth as calculated from measurement by digital caliper. Mean ± SEM (a); individual mice (b). c Immunohistochemical and quantification for granzyme B+ (GZMB) infiltrating cells in MC38 tumors from adoptive transfer recipient mice at day 26 after tumor implantation. ***p < 0.001; ****p < 0.0001.