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. 2021 Jun 3;11:11736. doi: 10.1038/s41598-021-91195-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiome composition of NSCLC patients and non-cancer controls in bronchoscopy samples. (A) Taxonomic composition of non-human sequences at phylum level in NSCLC patients and non-cancer controls in bronchoscopy samples. (B) The Shannon diversity index between NSCLC patients and non-cancer controls in bronchoscopy samples. Difference between sampling methods was determined by Student t test. *p < 0.05. (C) PCoA analysis of NSCLC patients and non-cancer controls in bronchoscopy samples. (D) The differential species between NSCLC patients and non-cancer controls in bronchoscopy samples were identified by Wilcoxon rank-sum test (p < 0.05). N non-cancer controls, T NSCLC patients.