Table 2.
Risk factors for 100-day mortality in multiple myeloma patients receiving ASCT.
| Predictive variables | Univariate analysis | Multivariate analysisa | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| HEPA group | 1.39 (0.44–4.37) | 0.576 | 1.65 (0.52–5.23) | 0.399 |
| Age ≥ 60 years | 0.93 (0.28–3.08) | 0.902 | ||
| Sex (male) | 1.17 (0.37–3.69) | 0.789 | ||
| Duration from MM to HSCT ≥ 180 days | 0.88 (0.26–2.92) | 0.832 | ||
| Comorbidities | ||||
| Atrial fibrillation | 4.28 (0.55–33.14) | 0.164 | ||
| Coronary artery disease | 5.80 (1.75–19.27) | 0.004 | 5.42 (1.63–18.02) | 0.006 |
| Liver cirrhosis | * | |||
| COPD | 0.89 (0.24–3.31) | 0.868 | ||
| Cerebrovascular accident | 1.54 (0.34–7.04) | 0.576 | ||
| Diabetes mellitus | 1.78 (0.57–5.61) | 0.324 | ||
| Hypertension | 1.97 (0.59–6.56) | 0.266 | ||
| ESRD | 5.46 (1.76–16.93) | 0.003 | 5.33 (1.70–16.68) | 0.004 |
| Heart failure | 1.85 (0.41–8.44) | 0.428 | ||
| Ischemic stroke | 1.11 (0.14–8.56) | 0.924 | ||
| Autoimmune disease | 1.96 (0.43–8.94) | 0.385 | ||
| Degree of urbanization | ||||
| Urban | Reference | |||
| Suburban | 1.03 (0.30–3.52) | 0.961 | ||
| Rural | 1.59 (0.20–12.93) | 0.664 | ||
| Income level | ||||
| Low | Reference | |||
| Intermediate | * | |||
| High | * | |||
ASCT autologous stem cell transplantation; HR hazard ratio; CI confidence interval; COPD chronic obstructive pulmonary disease; ESRD end-stage renal disease.
aAll factors with p < 0.1 in the univariate analysis were included in the Cox multivariate analysis. *Do not converge