Table 2.

Circulating microRNA composition of the tested signatures.

Signature Name	MicroRNA signature composition
The “8 microRNA Signature”	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-107 + hsa-miR-148a-3p + hsa-let-7i-5p + hsa-miR-19b-3p + hsa-miR-22-5p
Signature_1	hsa-let-7d-5p + hsa-miR-16-5p + hsa-miR-103a-3p + hsa-miR-199a-5p
Signature_2	hsa-let-7d-5p + hsa-miR-16-5p + hsa-miR-103a-3p + hsa-miR-22-3p + hsa-miR-30b-5p
Signature_3	hsa-let-7d-5p + hsa-miR-32-5p + hsa-miR-199a-5p + hsa-miR-142-3p + hsa-miR-22-5p
Signature_4	hsa-let-7d-5p + hsa-miR-148a-3p + hsa-let-7i-5p + hsa-miR-199a-5p + hsa-miR-451a
Signature_5	hsa-let-7d-5p + hsa-miR-148a-3p + hsa-let-7f.-1-3p + hsa-miR-199a-5p + hsa-miR-32-5p
Signature_6	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-148a-3p + hsa-let-7f.-1-3p + hsa-miR-32-5p
Signature_7	hsa-miR-16-5p + hsa-let-7d-5p + hsa-let-7i-5p + hsa-miR-19a-3p + hsa-let-7f.-1-3p + hsa-miR-1-3p
Signature_8	hsa-miR-16-5p + hsa-let-7i-5p + hsa-miR-19a-3p + hsa-miR-451a + hsa-miR-19b-3p + hsa-miR-32-5p
Signature_9	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-148a-3p + hsa-miR-19a-3p + hsa-miR-199a-5p + hsa-miR-22-3p
Signature_10	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-20a-5p + hsa-let-7i-5p + hsa-miR-1-3p + hsa-miR-32-5p
Signature_11	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-148a-3p + hsa-miR-93-5p + hsa-miR-451a + hsa-miR-1-3p + hsa-miR-22-5p
Signature_12	hsa-miR-16-5p + hsa-let-7d-5p + hsa-miR-103a-3p + hsa-miR-20a-5p + hsa-let-7f.-1-3p + hsa-miR-30b-5p + hsa-miR-590-5p + hsa-miR-22-3p