Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 3;12:3319. doi: 10.1038/s41467-021-23642-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a Schematic diagram illustrating the experimental design of Nron treatment in OVX mice. b Representative μCT images showing the 3D bone structures of mice femurs from Sham, OVX, OVX-Vector, and OVX-Nron group, (similar results were obtained in all mice, n = 6/group). Scale bar: 1 mm (all panels). c μCT measurements of BV/TV, Tb.N, and Tb.Th in femurs from Sham, OVX, OVX-Vector, and OVX-Nron group, (n = 6/group). d Representative TRAP staining images of mice femurs from Sham, OVX, OVX-Vector, and OVX-Nron group, (similar results were obtained in all mice, n = 6/group). Scale bar: 500 μm (upper panels); 100 μm (lower panels). e Quantification of osteoclastic metrics Oc.N/B.Pm and Oc.S/BS in subepiphyseal region of femurs in d, (n = 6/group). Data are presented as the means ± s.e.m. The significant differences between Sham/OVX-Vector/OVX-Nron treatment group with OVX group were determined by one-way ANOVA with Dunnett’s multiple comparisons test. Source data are provided as a Source Data file.