Table 2.
Arterial blood gas (ABG) values in 15-min intervals after the start of the trial intervention.
| PaCO2 | pH | PaO2 | |
|---|---|---|---|
| Baseline | 38.75 ± 3.65 | 7.44 ± 0.04 | 112.6 ± 24.0 |
| Hyp 0 min | 47.15 ± 4.81 | 7.34 ± 0.36 | 109.8 ± 15.8 |
| Hyp 15 min | 50.30 ± 5.02 | 7.31 ± 0.39 | 110.7 ± 17.0 |
| Hyp 30 min | 52.42 ± 4.13 | 7.30 ± 0.39 | 110.3 ± 14.5 |
| Hyp 45 min | 53.76 ± 5.17 | 7.29 ± 0.37 | 110.6 ± 14.2 |
| Hyp 60 min | 54.22 ± 5.27 | 7.29 ± 0.38 | 111.9 ± 14.0 |
| Hyp 75 min | 54.25 ± 5.06 | 7.28 ± 0.38 | 112.2 ± 16.8 |
| Hyp 90 min | 54.01 ± 5.51 | 7.29 ± 0.38 | 112.3 ± 12.4 |
| Hyp 105 min | 54.37 ± 4.66 | 7.29 ± 0.38 | 111.4 ± 12.2 |
| Hyp 120 min | 53.18 ± 7.16 | 7.29 ± 0.38 | 111.7 ± 13.7 |
After measurement of the baseline value, the respiratory minute volume (RMV) was reduced. The first ABG analysis after reducing the RMV was taken 5 min thereafter to exclude an exaggerated individual effect of the reduction of RMV. “Hyp 0 min” indicates a timepoint 15 min after the start of the study intervention and reduction of RMV. This value was then used to further modify the RMV to reach a target of 55 mmHg. (PaCO2 = arterial partial pressure of carbon dioxide, PaO2 = arterial partial pressure of oxygen, Hyp + # min indicates the time after the start of the hypercapnic trial intervention).