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. 2021 Jun 3;11:11676. doi: 10.1038/s41598-021-91112-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Regulation of CXCR4 expression in primary FL samples. (a, b) CXCR4 expression in CD10⁺/CD20⁺ cells of FL samples FL-B536, FL-LY86 and FL-LY221 at the start of the experiment, or after 6 h of treatment with anti-IgM or DC-SIGN-Fc, or left untreated (Ut) as a control. (a) Representative results obtained using sample FL-B536 and (b) summary for all samples (n = 3) analyzed. The graph shows mean (± SD) relative CXCR4 expression with values for control cells at 0 h set to 100%. The statistical significance of the indicated differences is shown (Paired t-test).