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. 2021 Jun 3;12(6):572. doi: 10.1038/s41419-021-03850-1

Fig. 5. BMS309403 improved kidney lesion by UUO.

Fig. 5

a Staining with HE, PAS, and MTS of kidney sections from obstructed (UUO) or sham-operated kidneys (control). Animals received BMS309403 (40 mg/kg for 8 days) or vehicle as indicated. n = 6 per group. b Western blot of whole-kidney lysates for FABP4, fibronectin, collagen-I, and α-SMA expression. GAPDH sets as loading control. c Fibronectin, collagen-I, and α-SMA mRNA expression by RT-qPCR. Schematic representation of quantitative data of indicated proteins. The transcripts normalized to Gapdh. Representative images from three independent experiments are shown above. **P < 0.01, ***P < 0.001, ns means no statistical significance. Scale bars: 25 μm.