Table 1.
Laboratory Findings.
| D0 | D2 | D4 | D6 | D14 | D60 | D120 | Reference Value | |
|---|---|---|---|---|---|---|---|---|
| Creatinine (mg/dL) | 1.87 | 1.24 | 1.32 | 1.01 | 0.83 | 0.77 | 0.9 | 0.9 to 1.3 mg/dL |
| Urea (mg/dL) | 57 | 80 | 90 | 93 | 30 | 34 | 30 | 17 to 43 mg/dL |
| Total bilirubin (mg/dL) | 0.7 | 0.76 | 0.94 | 0.84 | 0.57 | 0.67 | 0.71 | 0.3 to 1 mg/dL |
| TGO (U/L) | 74 | 54 | 57 | 56 | 40 | 20 | 18 | < 50 U/L |
| TGP (U/L) | 53 | 49 | 65 | 60 | 92 | 25 | 22 | < 50 U/L |
| LDH (U/L) | 756 | 541 | 490 | 540 | 359 | 150 | 143 | 140 to 271 U/L |
| Ferritin (ng/mL) | 2,611.7 | 2,006.7 | 2,049 | 2,466 | 1,109.7 | 281.8 | 206.8 | 23.9 a 336.2ng/mL |
| Troponina I (ng/mL) | 0.02 | 0.01 | 0.01 | 0.02 | 0 | 0 | 0 | <0.02 ng/mL |
| Lactate (nmol/L) | 1.7 | 2.4 | 3.4 | 2.4 | 1.4 | 1.2 | 1.3 | <1.8 nmol/L |
| C-reactive protein (mg/mL) | 25.3 | 12.0 | 4.6 | 3.5 | 0.5 | 0.6 | 0.4 | <5.0 mg/mL |
| D-dimer (ng/mL) | 11.400 | 3,545 | 3.977 | 3,897 | 1,675 | 369.7 | 141.27 | <554.0 ng/mL |
| Fibrinogen (mg/dL) | 353 | 267 | 229 | 250 | 197 | 418.39 | 299.9 | 200 to 395 mg/dL |
| KPTT (seconds) | 25.5 | 28.4 | 25.9 | 25.3 | 21.9 | 32.2 | _ | 24.9 a 37 seconds |
D0, pre-Infusion; D2, day after fisrt UC-MSC infusion; D4, day after second UC-MSC infusion; D6, day after third UC-MSC infusion; D14: 14 days after first UC-MSC infusion; D60, 60 days from first UC-MSC infusion; and D120, 120 days from first UC-MSC infusion.