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Distribution of CYP2D6 and CYP2C19 activity across the study sample of 50 depressive disorder patients, stratified by OCT1 genotype.
| 2 active OCT1 alleles (n = 27) | 1 active OCT1 allele (n = 17) | 0 active OCT1 alleles (n = 6) | |
|---|---|---|---|
| CYP2D6 activity | |||
| 3.0 | 0 (0%) | 1 (6%) | 0 (0%) |
| 2.0 | 10 (37%) | 8 (47%) | 3 (50%) |
| 1.5 | 8 (30%) | 2 (12%) | 1 (17%) |
| 1.0 | 7 (26%) | 5 (29%) | 2 (33%) |
| 0.5 | 2 (7%) | 1 (6%) | 0 (0%) |
| CYP2C19 activity | |||
| 2.0 | 16 (59%) | 11 (65%) | 4 (67%) |
| 1.0 | 10 (37%) | 6 (35%) | 2 (33%) |
| 0.0 | 1 (4%) | 0 (0%) | 0 (0%) |
