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. 2021 May 21;9:620565. doi: 10.3389/fped.2021.620565

Table 1.

The included studies.

References Design Sample size Scan size Age (years, mean ± SD) Sex female (%) OCTA
algorithm
Spherical equivalent (D) Type of amblyopia Study location No. of eyes intervention comparator
Zhang et al. (26) Cross-sectional 59 6 × 6 mm 7.86 ± 1.88 41.0% RTVue XR Avanti (SD) 4.97 ± 2.58 A China 22 21
Chen et al. (17) Longitudinal study 88 3 × 3 mm 8 (7, 9) 59.1% RTVue XR Avanti (SD) 4.44 ± 1.89 A China 22 66
Cinar et al. (18) Cross-sectional 74 3 × 3 mm 12 ± 4.2/13 ± 6.1 51.4% Triton DRI-OCT 3.80 ± 2.20 A Turkey 37 37
Gunzenhauser et al. (21) / 12 3 × 3 mm 6.5 66.7% RTVue XR Avanti (SD) / Mixed (A, AS) USA 12 /
Wong et al. (24) Cohort 1,075 6 × 6 mm 7.57 ± 1.20/
7.65 ± 0.97
55.4% Triton DRI-OCT −0.09 ± 4.34 Mixed (A, AS) China 30 1,045
Yilmaz Cinar and Ozkan (25) Cross-sectional 50 3 × 3/6 × 6 mm 12.60 ± 2.83/
11.64 ± 2.31
38.0% RTVueXR Avanti (SSADA) / Mixed (A, AS) Turkey 25 25
Araki et al. (15) Cross-sectional 15 3 × 3 mm 9.8 ± 3.4 73.3% NIDEK RS-3000, Advance (CODAA) / Mixed (A, AS) Japan 15 /
Chen et al. (16) Cross-sectional 151 3 × 3 mm 8 ± 0.52 45.7% RTVue XR (AngioVue version 2017.1.0.155) 4.53 ± 0.39 Mixed (A, AS) China 85 66
Demirayak et al. (19) Cross-sectional 38 3 × 3 mm 9.1 ± 2.73 55.3% RTVue XR (SSADA) 3.34 ± 0.90 Mixed (A, S) Turkey 17 21
Doguizi et al. (20) Cross-sectional 97 3 × 3 mm 13.7 ± 3.25 40.2% RTVue XR (SSADA) 5.31 ± 1.39 A Turkey 40 57
6 × 6 mm
Sobral et al. (23) Cross-sectional 26 3 × 3 mm 9.2 ± 2.84 53.8% RTVue XR (SSADA) 3.20 ± 1.85 Mixed (A, S) Portugal 26 26
Lonngi et al. (22) Case-control 59 3 × 3 mm 8.0 ± 4.0 56% RTVue XR (SSADA) 3.86 ± 19.88 Mixed (A, S) USA 13 50
6 × 6 mm

SD, standard deviation; OCTA, optical coherence tomography angiography; D, diopter; S, strabismic amblyopia; A, anisometropic amblyopia; AS, combined amblyopia patients with strabismus and anisometropia; SSADA, split-spectrum amplitude-decorrelation angiography algorithm; CODAA, complex OCT-signal difference analysis angiography.