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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Bone. 2020 Dec 23;144:115832. doi: 10.1016/j.bone.2020.115832

Fig. 6. Zfp467−/− had better resistance to high fat diet induced adipocytes accumulation and higher bone formation.

Fig. 6

16 weeks old female +/+ and −/− mice fed with LFD or HFD were weighted (body weight, inguinal fat weight, gonadal fat weight and brown fat weight) and screened using Lunar PIXImus Densitometer for body composition including (A) body mass, fat mass, and fat free mass, total and femoral areal bone mineral density (fBMD, aBMD), femoral areal bone mineral content (fBMC, aBMC); (B) Representative μCt images of tibia trabecular and cortical bone of 16 weeks old female +/+ and −/− mice fed with LFD or HFD. Trabecular microarchitecture was measured by μCT and trabecular bone volume/total volume (Tb.BV/TV), trabecular bone mineral density (Tb.BMD), connectivity density (Conn.D), trabecular number (Tb.N), trabecular separation (Tb.Sp), and structural modeling index (SMI) were calculated. Total area (Tt.Ar), cortical area/total area (Ct.Ar/Tt.Ar), cortical thickness (Ct.Th), marrow area (Ma.Ar), cortical porosity (Ct. Porosity), and cortical tissue mineral density (Ct.TMD) were also assessed. Data shown as mean ± SD, n=4–8 per group.