Table 1.
Beneficial effect of probiotic dairy products to human health.
| Product | Lactic acid bacteria strain | Functional benefit to human | References |
|---|---|---|---|
| Europe | |||
| Yohurt-Like beverage |
L. rhamnosus SP1, W. confusa DSM 20194, L. plantarum T6B10 |
Free amino acids and γ-Aminobutyric acid (GABA), polyphenols availability, antioxidant activity (up to 54%), and protein digestibility |
Lorusso et al., 2018 |
| Synbiotic yohurt | L. acidophilus, B. longum | Increase in HDL-cholesterol and improved LDL/HDL ratio | Kiessling et al., 2002 |
| Probiotic fresh cheese |
L. acidhophilus A9, B. bifidum A12, and L. paracasei A13 |
Immunomodulating capacity | Medici et al., 2004 |
| Edam cheese |
L. rhamnosus LC705, L. rhamnosus GG ATCC53103 (LGG) |
Decrease oral cavity risk by 21% | Ahola et al., 2002 |
| Capsule containing probiotics | L plantarum P17630 | Suppress Candida albicans of patients with vulvovaginal candidiasis (VVC) | Seta et al., 2014 |
| Supplement | L. casei Shirota | Improve immune status of athletes | Gleeson et al., 2016 |
| Supplement | L. subtilis, S. faecium | Restoration of bowel flora and improvement of lipopolysaccharide in patients with alcoholic hepatitis | Han et al., 2015 |
| Asia | |||
| Iranian traditional cheese | L. plantarum | Stomach ulcer | Nasrabadi et al., 2011 |
| Iranian probiotic yogurt | L. brevis | Wound, diabetes type II | Ejtahed et al., 2011 |
| Probiotic yogurt |
L. delbrueckii subsp. bulgaricus and S.thermophilus. B. animalis subsp. lactis Bb12 (DSM 10140) and L. acidophilus strain La5 |
Decrease in HbA1c and TNF-α levels | Mohamadshahi et al., 2014 |
| Probiotic supplement |
B. bifidum, L. casei, L. acidophilus 2 |
Glycemic control, HDL-cholesterol, total-/HDL-cholesterol ratio, biomarkers of inflammation, and oxidative stress in diabetic patients with CHD | Raygan et al., 2018 |
| Yak milk | L. casei SB27 | Inhibit the proliferation of HT-29 colorectal cancer cells and up-regulated the 7expressions of Bad, Bax, Caspase-3, and−8 genes | Di et al., 2017 |
| Tibetan kefir | L. plantarum YW11 | Increased the content of short-chain fatty acids, antioxidant, and gut microbiota regulating activities | Zhang et al., 2017 |
| Fermented milk |
L. delbrueckii ssp. bulgaricus SRFM-1 | Antioxidant | Tang et al., 2017 |
| Fermented milk | L. rhamnosus SD11 | Oral health by reducing salivary levels mutans streptococci | Rungsri et al., 2017 |
| Iranian traditional cheese | L. plantarum | Enhanced gastric ulcer healing via stimulating immune system and fibroblast increasing | Nasrabadi et al., 2011 |
| Kurut (Tibet traditional fermented milk) | L helveticus H9 | Antihypertensive | Chen et al., 2014 |
| Traditional fermented yak's milk (Tibet, China) | L. coryniformis subsp torquens T3L | Immunomodulating effect | Tuo et al., 2011 |
| Kefir (Tibet, Kaukasian mountain, China) | L. kefiranofaciens | Antibacterial, hypocholesterolemic, antihypertensive, anti-inflammatory, anti-diabetic, antioxidant, anti-carcinogenic, anti-allergenic activities | Rosa et al., 2017 |
| Chinese sauerkraut | L. plantarum S4-1 | Reduce serum cholesterol level | Yu et al., 2013 |
| Xueo (traditional fermented yak milk), China | L. fermentum SCA52 | Antimicrobial activity | Ao et al., 2012 |
| Fermented milk (Kefir) Japan | Lactobacillus/Lactococcus sp. | Anti-Obesity, and anti-non-alcoholic fatty liver disease activity |
Kim et al., 2017 |
| Fermented milk product (Japan) |
L. helveticus (probiotics) |
Improved the cognitive function of healthy adults | Ohsawa et al., 2018 |
| Koumiss (China) | L. paracasei supsp. paracasei M5L | Immunomodulating effect | Tuo et al., 2011 |
| Fermented Milk (China) | L. paracasei Jlus66 | Protecting from Nonalcoholic fatty liver disease (NAFLD) | Ye et al., 2017 |
| Fermented milk enriched with gamma-Aminobutyric acid (China) | L. brevis and L. plantarum | Promote relaxation and reduce anxiety | Yu et al., 2020 |
| Dadih (Fermented Buffalo milk) Indonesia | L. plantarum IS-10506 | Therapy of children with atopic dermatitis | Prakoeswa et al., 2017 |
| Dahi (Yogurt like) India Pakistan |
L. acidophilus LA 02, L. delbrueckii subsp. bulgaricus |
Reduce functional constipation, prevention of recurrence of vulvovaginal candidiasis | Mitelmão et al., 2021 |
| Koumiss (Mare's milk) Central Asia | L. fermentum SM-7 | Cholesterol-Lowering ability for hypercholesterolemia treatment | Thumu and Halami, 2020 |
| Yakult |
L. casei Shirota and B. breve Yakult |
Improve symptoms and decrease hydrogen production intake in lactose-intolerant patients | Almeida et al., 2012 |
| America | |||
| Milk Kefir | L. kefiri | Down-Regulate expression of pro-inflammatory mediators and increase anti-inflammatory molecules in the gut immune system | Rosa et al., 2017 |
| Fermented milk (yogurt) | L. helveticus R389 | Delayed breast tumor growth by decreasing IL-6 and increasing IL-10 in serum | Leblanc and De Perdigo, 2010 |
| Fermented milk |
L. rhamnosus GG and S. boulardii |
To prevent antibiotic-associated diarrhea and to treat acute infectious diarrhea | Barnes and Yeh, 2015 |
| Fermented milk | L. acidophilus and L. casei | Prevention of antibiotic-associated diarrhea | Beausoleil et al., 2007 |
| Fermented milk (Kefir) Argentina | L. paracasei CIDCA8339 | Antiinflamatory effect | Bengoa et al., 2019 |
| Africa | |||
| Yogurt |
L. rhamnosus GR-1 and L. reuteri RC-14 |
Increased CD4 cell count, resolved diarrhea, flatulence, and nausea of HIV/AIDS patients | Anukam et al., 2008 |
| Fermented milk product (lait caillé) from Northern Senegal | L. rhamnosus yoba 2012 | Health-Promoting probiotic, prevalence of malnutrition | Parker et al., 2018 |
| Ghanaian traditionally fermented milk | E. faecium, L. fermentum, L. plantarum, and P. acidilactici | Antimicrobial pathogent/Antibiotic activity | Motey et al., 2021 |