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. 2021 May 21;11:609548. doi: 10.3389/fonc.2021.609548

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Copyright © 2021 Li, He, Ye, Ye, He, Chen and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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p62 and LC3B protein expression as determined by immunohistochemistry assay. (A, B) High p62 (A, scale bar 100µm) and LC3B (B) expression at magnification ×100 (left) and ×200 (right). (C, D) Low p62 (C) and LC3B (D) expression at magnification ×100 (left) and ×200 (right). (E, F) High p62 expression was associated with shorter progression-free survival rates (E) and overall survival rates (F) in patients with bone metastasis of lung adenocarcinoma.