TABLE 4.

Results of robust mixed linear regression model for predictors of SLEDAI-2K. Individual Patient ID was included as random effect in the model. Predictor values were measured at all timepoints.

Dependent: SLEDAI-2K
Predictors	Estimate	Std. error	t. value	p
(Intercept)	11.4386	1.1960	9.5644	<0.001
Month 6	−2.9902	0.5108	−5.8544	<0.001
Month 12	−3.3201	0.5197	−6.3886	<0.001
C3	−0.0574	0.0140	−4.1083	0.0004
sTACI	−0.0002	0.0001	−2.3424	0.0285

MODEL FIT: AIC = 300.13, BIC = 315.02 Pseudo-R² (fixed effects) = 0.47 Pseudo-R² (total) = 0.63. In bold p ≤ 0.050. SLEDAI-2K score, systemic lupus erythematosus disease activity index 2,000; sTACI: soluble transmembrane activator and calcium-modulator and cyclophilin ligand interactor; C3: complement factor 3.