TABLE 2.
Differently expressed miRNAs between APP/PS1 and WT mice.
| Name | AD_ readcount | Ctrl_ readcount | log2FoldChange | p-value |
| Up-regulated | ||||
| mmu-miR-6481 | 18.68982 | 4.322652 | 1.3238 | 0.001602 |
| mmu-miR-29b-3p | 495.2749 | 211.0125 | 1.1645 | 8.24E-09 |
| mmu-miR-29a-3p | 118111.2 | 54394.02 | 1.0745 | 2.69E-10 |
| mmu-miR-344d-3-5p | 319.5235 | 148.8742 | 0.97566 | 0.000481 |
| mmu-miR-3074-1-3p | 185.8845 | 102.5404 | 0.8147 | 7.04E-05 |
| mmu-miR-29c-3p | 139.5045 | 76.32593 | 0.7979 | 0.001251 |
| mmu-miR-24-1-5p | 188.332 | 105.8336 | 0.78842 | 0.000132 |
| mmu-miR-129b-5p | 2732.962 | 1536.956 | 0.78262 | 0.000131 |
| mmu-miR-3102-3p | 962.5197 | 569.701 | 0.71115 | 0.000643 |
| mmu-miR-222-3p | 18468.63 | 11009.11 | 0.69991 | 0.000922 |
| mmu-miR-664-3p | 1197.966 | 725.9918 | 0.68802 | 0.000265 |
| mmu-miR-221-5p | 2240.683 | 1361.592 | 0.68249 | 0.000392 |
| mmu-miR-3068-5p | 340.8997 | 209.7466 | 0.66796 | 0.000222 |
| mmu-miR-221-3p | 16177.18 | 10037.58 | 0.65584 | 0.00042 |
| mmu-let-7e-3p | 405.1511 | 275.5497 | 0.53313 | 0.001513 |
| mmu-miR-344b-3p | 1073.644 | 738.0082 | 0.52116 | 0.00206 |
| Down-regulated | ||||
| mmu-miR-298-5p | 333.5885 | 1352.94 | −1.9447 | 4.46E-31 |
| mmu-miR-1197-3p | 4.053018 | 23.29665 | −1.7052 | 2.61E-05 |
| mmu-miR-1983 | 392.6913 | 1361.133 | −1.6874 | 3.13E-16 |
| mmu-miR-412-5p | 473.496 | 1532.112 | −1.6259 | 5.95E-21 |
| mmu-miR-298-3p | 2.126654 | 17.24759 | −1.6224 | 0.000178 |
| mmu-miR-344f-3p | 155.3415 | 482.7177 | −1.5446 | 2.33E-14 |
| mmu-miR-881-3p | 4.187014 | 22.05614 | −1.5438 | 0.000216 |
| mmu-miR-449a-5p | 12.80265 | 50.6019 | −1.5218 | 2.61E-05 |
| mmu-miR-871-3p | 9.149676 | 31.4921 | −1.3645 | 0.000292 |
| mmu-miR-669e-5p | 3.739892 | 16.45383 | −1.35 | 0.001142 |
| mmu-miR-6977-3p | 4.825787 | 22.62498 | −1.3302 | 0.001815 |
| mmu-miR-666-5p | 918.8775 | 2496.094 | −1.3144 | 1.17E-07 |
| mmu-miR-296-3p | 126.8954 | 339.053 | −1.2638 | 3.31E-06 |
| mmu-miR-704 | 11.4574 | 33.68301 | −1.2305 | 0.000545 |
| mmu-miR-323-3p | 3855.472 | 8182.974 | −1.0241 | 4.28E-07 |
| mmu-miR-503-3p | 34.76984 | 76.19848 | −1.0154 | 0.000105 |
| mmu-miR-412-3p | 108.1681 | 228.1667 | −0.96854 | 0.000283 |
| mmu-miR-322-3p | 262.6622 | 558.4182 | −0.94468 | 0.001368 |
| mmu-miR-3078-5p | 73.46593 | 127.4599 | −0.75059 | 0.000458 |
| mmu-miR-351-5p | 221.2018 | 378.9669 | −0.73994 | 0.000168 |
| mmu-miR-487b-3p | 1994.151 | 3127.145 | −0.62393 | 0.000249 |
| mmu-miR-467a-5p | 901.2772 | 1233.437 | −0.44142 | 0.001861 |
| mmu-miR-467b-5p | 901.2772 | 1233.437 | −0.44142 | 0.001861 |