Skip to main content
. 2021 Jun;191(6):1020–1035. doi: 10.1016/j.ajpath.2021.02.018

Figure 7.

Figure 7

Dkk1 knockdown inhibits extracellular matrix in primary human trabecular meshwork (HTM) cells. HTM 2180 (A), HTM71FOS (B), and HTM2023 (C) cells were transfected with nontargeting (NT) siRNA/Dkk1 siRNA. The cells were treated with 0.1% ethanol (EtOH) or 100 nmol/L dexamethasone (Dex) for 3 days, and conditioned medium (CM) and whole cell lysate (WCL) were harvested for Western immunoblotting. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) served as a loading control for WCL. FN, fibronectin.